225 Binney Street in Cambridge, Massachusetts is home to Biogen’s six-story world headquarters. The property incorporates two renovated historic buildings combined with a new six-story office building, totaling 325,000 SF overall. The exterior consists of a glass and masonry façade. The structural system involves cast-in-place concrete cores built around the building’s stairs and elevators to provide lateral stability, with structural steel frames for gravity framing support. 225 Binney Street also includes two stories of below-grade parking excavated below the new construction.